Tenascin-C in the early lung cancer tumor microenvironment promotes progression through integrin activation and FAK
Shiela C. Samson, Anthony Rojas, Rebecca G. Zitnay, Keith R. Carney, Wakeiyo Hettinga, Mary C. Schaelling, Delphine Sicard, Wei Zhang, Melissa Gilbert‐Ross, Grace Kho Dy, Michael J. Cavnar, Muhammad Furqan, Robert F. Browning Jr, Abdul Rafeh Naqash, Bryan Paul Schneider, , Michelle C. Mendoza
This study shows that Tenascin-C promotes early lung cancer progression by activating integrins and FAK in mouse models and human lung adenocarcinomas.
bioRxiv · Sep 17, 2024 · PreprintCancer Biology