Adam I. Marcus

The paper presents a computational model of tumor invasion, identifying four invasion phenotypes and showing that multimodal invasion is most common under specific mechanical conditions.

This study shows that Tenascin-C promotes early lung cancer progression by activating integrins and FAK in mouse models and human lung adenocarcinomas.

TASI quantifies tumor spheroid dynamics through spatiotemporal segmentation, feature extraction, modeling, and statistical analysis, demonstrating its utility in analyzing non-small cell lung cancer spheroids.