PKN2 regulates cell-junctions to limit colitis
Jack C. Henry, Ashley Campbell, Prerana Huddar, Joanne Sewell, Shinelle Menezes, Adam M. Passman, Kane Smith, Shannah McGauran, Ivan Quétier, Meng‐Lay Lin, Marnix Jansen, Neil Q. McDonald, Trevor A. Graham, Stuart McDonald, Angus J.M. Cameron
This study identifies PKN2 as a regulator of tight junctions that limits colitis and colorectal cancer by maintaining intestinal barrier integrity during inflammation.
bioRxiv · Jun 28, 2026 · PreprintCell Biology