Wayne A. Hendrickson

This study identifies the RY12 domain of RyR1 as an ADP sensor and reveals dantrolene's binding mechanism through cryo-EM structures.

This paper identifies a small molecule inhibitor of PPARγ acetylation that improves insulin sensitivity and browning of white adipose tissue without the side effects of traditional PPARγ agonists.

This study shows that the CD4 mimetic CJF-III-288 enables anti-CoRBS antibodies to mediate ADCC by stabilizing an asymmetric open Env conformation.

The paper presents the cryo-EM structure of a nematode LGR dimer, providing insights into the evolution and function of glycoprotein hormone receptors.