Author

Silviu-Alin Bacanu

Virginia Commonwealth University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 3 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Assay:GWAS summary statistics· 3 Research Focus:benchmarking· 2 Organism:human· 2 Research Focus:variant effect prediction· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Aaron J. GorelikiD· 1 shared Adam X Maihofer· 1 shared Adriana LoriiD· 1 shared Akitoyo HishimotoiD· 1 shared Alexander S Hatoum· 1 shared Alexis C. EdwardsiD· 1 shared Alice BrauniD· 1 shared Amanda L. DobbyniD· 1 shared

Activity by Year

2015-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Aaron J. GorelikORCID

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Author profile →

4 papers

Recent·Most cited

Genome-wide association studies identify 77 loci for suicidality and provide novel biological insights

Sarah M. C. Colbert, Maria Koromina, Alexander S Hatoum, Mallory Stephenson, Alexis C. Edwards, Emma C. Johnson, Xuejun Qin, Andrey A Shabalin, Lucas T Ito, Kevin S O’Connell, Arvid Harder, Jens Hjerling-Leffler, Min Ji Kim, Ikuo Otsuka, Laura Vilar‐Ribó, , Bharath Holla

This study identifies 77 genetic loci associated with suicidality through genome-wide association analyses across multiple cohorts and provides biological insights into its genetic architecture.

medRxiv · Oct 22, 2025 · PreprintGenetic & Genomic Medicine

Analysis of Genetically Regulated Gene Expression identifies a trauma type specific PTSD gene, SNRNP35

Laura M. Huckins, Michael S. Breen, Chris Chatzinakos, Jakob Hartmann, Torsten Klengel, Ana Carolina da Silva Almeida, Amanda L. Dobbyn, Kiran Girdhar, Gabriel E. Hoffman, Claudia Klengel, Mark W. Logue, Adriana Lori, Filomene G. Morrison, Hoang T. Nguyen, Yongjin Park, , Nikolaos P. Daskalakis

The paper identifies SNRNP35 as a trauma type-specific PTSD gene through analysis of genetically regulated gene expression in PTSD cases and controls.

bioRxiv · Mar 19, 2019 · PreprintGenetics

QCAT: testing causality of variants using only summary association statistics

Donghyung Lee, T. Bernard Bigdeli, Vladimir I. Vladimirov, Ayman H. Fanous, Silviu-Alin Bacanu

QCAT tests causality of genetic variants using summary association statistics without assuming causal variants are catalogued.

bioRxiv · Aug 31, 2016 · PreprintGenetics

FIQT: a simple, powerful method to accurately estimate effect sizes in genome scans

Tim B. Bigdeli, Donghyung Lee, Brien P. Riley, Vladimir Vladimirov, Ayman H. Fanous, Kenneth S. Kendler, Silviu-Alin Bacanu

FIQT estimates Z-score means from genome scans more accurately and efficiently than existing methods, improving risk prediction in schizophrenia studies.

bioRxiv · May 13, 2015 · PreprintGenetics