Author

Ikuo Otsuka

Kobe UniversityORCID 0000-0002-2831-9158Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:GWAS summary statistics· 4 Approach:statistical model· 4 Research Focus:GWAS / association mapping· 3 Organism:human· 3 Research Focus:benchmarking· 1 Research Focus:polygenic risk· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Akitoyo HishimotoiD· 4 shared Alexis C. EdwardsiD· 3 shared Philip A. P. M. GorwoodiD· 3 shared Swapnil AwasthiiD· 3 shared Wei J. CheniD· 3 shared Abigail D. PowersiD· 2 shared Adrián I. CamposiD· 2 shared Adriana LoriiD· 2 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersGenetic & Genomic Medicine

Akitoyo HishimotoORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Genome-wide association studies identify 77 loci for suicidality and provide novel biological insights

Sarah M. C. Colbert, Maria Koromina, Alexander S Hatoum, Mallory Stephenson, Alexis C. Edwards, Emma C. Johnson, Xuejun Qin, Andrey A Shabalin, Lucas T Ito, Kevin S O’Connell, Arvid Harder, Jens Hjerling-Leffler, Min Ji Kim, Ikuo Otsuka, Laura Vilar‐Ribó, , Bharath Holla

This study identifies 77 genetic loci associated with suicidality through genome-wide association analyses across multiple cohorts and provides biological insights into its genetic architecture.

medRxiv · Oct 22, 2025 · PreprintGenetic & Genomic Medicine

Genome-wide association study meta-analysis of suicide attempt identifies twelve genome-wide significant loci and implicates genetic risks for specific health factors

Anna R. Docherty, Niamh Mullins, Allison E. Ashley‐Koch, Xuejun Qin, Jonathan R. I. Coleman, Andrey A. Shabalin, Jooeun Kang, Balasz Murnyak, Frank R. Wendt, Mark J. Adams, Adrián I. Campos, Emily DiBlasi, Janice M. Fullerton, Henry R. Kranzler, Amanda V. Bakian, , Laura M. Thornton

This paper conducts a multi-ancestry GWAS meta-analysis of suicide attempt, identifying 12 genome-wide significant loci and finding shared genetic risks with ADHD, smoking, and risk tolerance.

medRxiv · Jul 3, 2022 · PreprintGenetic & Genomic Medicine

Improving Polygenic Prediction in Ancestrally Diverse Populations

Yunfeng Ruan, Kuang Lin, Yen‐Chen Anne Feng, Chia‐Yen Chen, Max Lam, Zhenglin Guo, Stanley Global Asia Initiatives, Yong Min Ahn, Kazufumi Akiyama, Makoto Arai, Ji Hyun Baek, Wei J. Chen, Young‐Chul Chung, Gang Feng, Kumiko Fujii, , Tian Ge

This paper introduces PRS-CSx, a method that improves polygenic prediction across ancestrally diverse populations by integrating GWAS summary statistics and sharing genetic effects.

Nature Genetics · May 1, 2022Peer-reviewedGenetic & Genomic Medicine

Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

Niamh Mullins, Jooeun Kang, Adrián I. Campos, Jonathan R. I. Coleman, Alexis C. Edwards, Hanga Galfalvy, Daniel F. Levey, Adriana Lori, Andrey A. Shabalin, Anna Starnawska, Mei-Hsin Su, Hunna J. Watson, Mark J. Adams, Swapnil Awasthi, Michael J. Gandal, , DAVID L. BRAFF

This study identifies genetic loci associated with suicide attempts and shows shared genetic architecture with psychiatric disorders and non-psychiatric risk factors.

Biological Psychiatry · Sep 8, 2021Peer-reviewedGenetic & Genomic Medicine