Author

Stef Van den Bergh

Universitair Ziekenhuis Leuven

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Alexandra Bacquelaine VelosoiD· 1 shared Daan DierickxiD· 1 shared Félicien Renard· 1 shared Heidi SegersiD· 1 shared Ilan Bischops· 1 shared Jan CoolsiD· 1 shared Jente M. Schoenaker· 1 shared Kris JacobsiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alexandra Bacquelaine VelosoORCID

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1 paper

Recent·Most cited

Dual targeting of EZH2 and Histone Deacetylases in hematological malignancies promotes transcriptional and metabolic deregulation leading to ferroptosis

Alexandra Bacquelaine Veloso, Thomas Slegers, Jente M. Schoenaker, Sofie Demeyer, Stef Van den Bergh, Margo Aertgeerts, Krista Roberta Verhoeft, Yilke Schoenmaekers, Nienke Meeuws, Ilan Bischops, Félicien Renard, Lien Boogaerts, Nicole Mentens, Olga Gielen, Kris Jacobs, , Marlies Vanden Bempt

This study shows that targeting EZH2 and HDACs together induces ferroptosis in hematological malignancies by upregulating cholesterol biosynthesis and causing metabolic stress.

bioRxiv · Mar 3, 2024 · PreprintCancer Biology