Stefan Choy

CRISPR screening reveals genetic regulators associated with the evolution of eye degeneration

The paper identifies genetic regulators of eye degeneration in cavefish using CRISPR screening and functional assays.

Analysis of multi-trait evolution across independently evolved cavefish populations reveals shared and independent evolution of suites of cave-associated traits

The paper examines multi-trait evolution in cavefish, finding shared and distinct genetic mechanisms and evidence for pleiotropy or linkage in trait evolution.

Automated behavioral profiling using neural networks reveals differences in stress-like behavior between cave and surface-dwelling Astyanax mexicanus

The paper uses neural networks to analyze stress-like behaviors in cave and surface-dwelling Astyanax mexicanus, finding differences in freezing, bottom-dwelling, and hyperactivity.

Automated profiling of social behaviors to assess the genetic basis of evolution of aggressive behaviors in A. mexicanus

The paper develops an automated machine learning pipeline to quantify aggression-related behaviors in A. mexicanus and finds behavioral differences between surface and cave fish, with correlations suggesting shared genetic mechanisms.

Mutations in the albinism gene oca2 alter vision-dependent prey capture behavior in the Mexican tetra

This study shows that oca2 mutations in Mexican tetra affect prey capture behavior, with albino fish using vision in light and lateral line in dark, impacting competitive success in different environments.