Author

Steffen Pfalzgraf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Daniela BenderiD· 1 shared Eberhard HildtiD· 1 shared Iris Li· 1 shared Iuliia Ferling· 1 shared Kerstin K. SchwickertiD· 1 shared Kevin SchwickertiD· 1 shared Lanhui Qiu· 1 shared Lea Moutounet· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Daniela BenderORCID

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2 papers

Recent·Most cited

Late stages of the Zika virus life cycle are impaired by a selective TRPML2 agonist

Kerstin K. Schwickert, Mirco Glitscher, Daniela Bender, Robin Murra, Kevin Schwickert, Steffen Pfalzgraf, Tanja Schirmeister, Ute A. Hellmich, Eberhard Hildt

This study shows that the TRPML2 agonist ML2-SA1 inhibits late stages of Zika virus replication by affecting genome replication and intracellular cholesterol distribution.

bioRxiv · Feb 1, 2024 · PreprintCell Biology

Reactive oxygen species suppress phagocyte surveillance by oxidizing cytoskeletal regulators

Iuliia Ferling, Steffen Pfalzgraf, Lea Moutounet, Lanhui Qiu, Iris Li, Yuhuan Zhou, Sergio Grinstein, Spencer A. Freeman

This study shows that reactive oxygen species (ROS) from IgG-opsonized targets suppress phagocyte surveillance by oxidizing cytoskeletal regulators, leading to cell compaction and podosome disassembly.

bioRxiv · Jan 31, 2024 · PreprintCell Biology