Cell BiologyAging CellPeer-reviewed
Senescent myoblasts exhibit ROS-dependent Akt-mTORC1 dysregulation and are susceptible to reductive stress-induced cell death.
Vladimir Belhac, Alex Dillingham, Emilia Coward…·Neil R. W. Martin
This study identifies ROS-dependent Akt-mTORC1 dysregulation in senescent myoblasts and shows antioxidants can suppress inflammation and promote differentiation but also induce cell death.
DOI 10.1111/acel.70589