Author

Stephanie I. Walter

Seattle Children's Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Elizabeth R. LawloriD· 3 shared Nicolas M. GarciaiD· 3 shared Darleen S. Tu· 2 shared Emma D. WrenniD· 2 shared Aaron K OlsoniD· 1 shared April Ann ApfelbaumiD· 1 shared Aya MiyakiiD· 1 shared Erolcan SayariD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersCancer Biology

Elizabeth R. LawlorORCID

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3 papers

Recent·Most cited

Menin inhibition impairs metastatic colonization of Ewing sarcoma

Katherine A. Braun, Nicolas M. Garcia, Mohamed Amin Ahmed, Darleen S. Tu, Stephanie I. Walter, Emma D. Wrenn, Megan E. B. Dean, Neerja Katiyar, Elizabeth R. Lawlor

This study shows Menin inhibition reduces metastatic colonization of Ewing sarcoma in vivo by disrupting MYC target gene expression and Menin:MYC interactions.

JCI Insight · Sep 1, 2026Peer-reviewedCancer Biology

Autocrine TGFβ2 enforces a transcriptionally hybrid cell state in Ewing sarcoma

Emma D. Wrenn, Jacob C Harris, April Ann Apfelbaum, Jonah R. Valenti, Patricia A. Lipson, Stephanie I. Walter, Nicolas M. Garcia, Aya Miyaki, Steven C. Chen, Jim M. Olson, Jason P. Price, Kelly M. Bailey, Elizabeth R. Lawlor

The paper identifies TGFβ2 as a driver of a hybrid transcriptional state in Ewing sarcoma cells, promoting metastasis through ECM deposition and invasion.

Science Advances · Jan 21, 2026Peer-reviewedCancer Biology

Determining preclinical safety of Aclarubicin in pediatric malignancies

Darleen S. Tu, Aaron K Olson, Kimberly S. Waggie, Nicolas M. Garcia, Virginia J. Hoglund, Stephanie I. Walter, Jenna R. Rosinski, Harini Sadeeshkumar, Radhika A. Patel, Erolcan Sayar, Michael C. Haffner, Lisa Maves, Jacques Neefjes, Jay F. Sarthy, Elizabeth R. Lawlor, Shireen S. Ganapathi

This study evaluates Aclarubicin's safety and efficacy in pediatric cancer models, finding it effective with reduced genotoxicity and cardiotoxicity compared to doxorubicin.

Pediatric Blood & Cancer · Nov 26, 2025Peer-reviewedCancer Biology