Author

Subhashini Madhuranath

Weill Cornell Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Developmental Biology· 2

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Christopher M. UyeharaiD· 2 shared Effie ApostolouiD· 2 shared Matthias StadtfeldiD· 2 shared Alexander PolyzosiD· 1 shared Alexandros Polyzos· 1 shared Anna‐Katerina HadjantonakisiD· 1 shared Clayton SchwarziD· 1 shared Daniel Medina-CanoiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

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10 top collaborators · 39 mutual co-author links

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2 shared papersDevelopmental Biology

Christopher M. UyeharaORCID

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2 papers

Recent·Most cited

Coordinated repression of totipotency-associated gene loci by histone methyltransferase EHMT2 through binding to LINE-1 regulatory elements

Kaushiki Chatterjee, Christopher M. Uyehara, Kritika Kasliwal, Subhashini Madhuranath, Laurianne Scourzic, Alexandros Polyzos, Effie Apostolou, Matthias Stadtfeld

The paper identifies EHMT2's role in repressing totipotency-associated gene loci in mESCs by binding to LINE-1 elements and modulating gene expression during the mESC-to-2CLC transition.

bioRxiv · Dec 18, 2024 · PreprintDevelopmental Biology

Transcriptional remodeling by OTX2 directs specification and patterning of mammalian definitive endoderm

Ly-Sha Ee, Daniel Medina-Cano, Christopher M. Uyehara, Clayton Schwarz, Emily Goetzler, Eralda Salataj, Alexander Polyzos, Subhashini Madhuranath, Todd Evans, Anna‐Katerina Hadjantonakis, Effie Apostolou, Tommy Vierbuchen, Matthias Stadtfeld

This study identifies OTX2 as a critical regulator of definitive endoderm specification and gut patterning through chromatin remodeling and signaling pathway regulation.

bioRxiv · May 30, 2024 · PreprintDevelopmental Biology