Author

Sumit Pareek

The University of Texas at Austin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2

Frequent Co-Authors

Annalee W. NguyeniD· 2 shared George GeorgiouiD· 2 shared Jason S. McLellaniD· 2 shared Jennifer A. MaynardiD· 2 shared Ahlam N. QerqeziD· 1 shared Akaash Kumar MishraiD· 1 shared Alexandra SchäferiD· 1 shared Alison G. LeeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Annalee W. NguyenORCID

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Author profile →

2 papers

Recent·Most cited

Broad Sarbecovirus Neutralization by an S2-Directed Plasma Antibody Defines a New Site of Vulnerability in SARS-like Viruses

Douglas R. Townsend, Ling Zhou, Michael L. Mallory, William N. Voss, Sean A. Knudson, Cory M. Acreman, John M. Powers, Miranda L. Hubbard, Alexandra Schäfer, Nicholas Catanzaro, David R. Martinez, Sumit Pareek, Connor M. Mullins, Annalee W. Nguyen, Jennifer A. Maynard, , Jason J. Lavinder

The paper identifies a broadly neutralizing antibody targeting the S2 subunit of sarbecoviruses, revealing a conserved site of vulnerability in the spike protein.

bioRxiv · Jun 8, 2026 · PreprintImmunology

Selective decoupling of IgG1 binding to viral Fc receptorsrestores antibody-mediated NK cell activation against HCMV-infected cells

Ahlam N. Qerqez, Katja Hoffmann, Alison G. Lee, Sumit Pareek, Kelli Hager, Akaash Kumar Mishra, George Delidakis, Kirsten Bentley, Lauren E. Kerr-Jones, Mica Cabrera, Truong Nguyen, Rebecca L. Göttler, Amjad A. Chowdhury, Philipp Kolb, Hartmut Hengel, , Jennifer A. Maynard

This paper engineers IgG1 antibodies with modified Fc domains to resist viral Fc receptor binding, enhancing NK cell activation and reducing HCMV spread in infected cells.

Cell Reports · Dec 1, 2025Peer-reviewedImmunology