PIN1 Drives Cellular Plasticity and Immune Modulation in Chronic Pancreatitis
Vidhi M. Shah, Alexandra Q. Bartlett, Canping Chen, Aubry Matter, Alexander Smith, Hayley Zimny, Xiaoyan Wang, Colin J. Daniel, Jenny Eng, Syber Haverlack, Isaac Youm, Motoyuki Tsuda, Nicholas L. Calistri, Matthew Reyer, Terry K. Morgan, , Rosalie C. Sears
This study shows PIN1 promotes cellular plasticity and immune changes in chronic pancreatitis, with genetic or pharmacological inhibition reducing disease severity.
bioRxiv · May 13, 2025 · PreprintCell Biology