Author

T. A. Mendum

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

B. S. Hall· 1 shared F. J. Salguero· 1 shared G. Panis· 1 shared G. R. Stewart· 1 shared J. Diaz Delgado· 1 shared J. Newcombe· 1 shared J. Nitschke· 1 shared J. Prados· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMicrobiology

B. S. Hall

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Temporal genome-wide fitness analysis of Mycobacterium marinum during infection reveals genetic requirement for virulence and survival in amoebae and microglial cells

L. H. Lefrancois, J. Nitschke, G. Panis, J. Prados, R. E. Butler, T. A. Mendum, N. Hanna, G. R. Stewart, T. Soldati

This study uses Tn-Seq to identify essential genes for Mycobacterium marinum survival in amoebae and microglial cells, revealing metabolic and virulence gene requirements during infection.

bioRxiv · Mar 22, 2023Microbiology

Mycolactone causes destructive Sec61-dependent loss of the endothelial glycocalyx and vessel basement membrane: a new indirect mechanism driving tissue necrosis in Mycobacterium ulcerans infection

L. T.-H. Hsieh, B. S. Hall, J. Newcombe, T. A. Mendum, S. Santana-Varela, Y. Umrania, M. J. Deery, W. Q. Shi, J. Diaz Delgado, F. J. Salguero, R. E. Simmonds

This study shows mycolactone causes endothelial glycocalyx and basement membrane loss via Sec61-dependent mechanisms, leading to vascular dysfunction and tissue necrosis in Buruli ulcer.

bioRxiv · Feb 21, 2023Microbiology