Author

T. Fujisawa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Microbiology· 1 Zoology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Approach:deep learning· 1 Research Focus:ecology & biodiversity· 1

Frequent Co-Authors

Y. Ito· 2 shared A. P. Vogler· 1 shared A. Papadopoulou· 1 shared B. Chang· 1 shared E. Meramveliotakis· 1 shared H. Ichijo· 1 shared H. Noma· 1 shared I. Naguro· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersMicrobiology

Y. Ito

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Pathophysiological Significance of Impaired KAT7-Dependent Histone H3K14 Acetylation During Zinc Deficiency

T. Fujisawa, S. Takenaka, L. Maekawa, T. Kowada, T. Matsui, S. Mizukami, Y. Kato, M. Suzuki, H. Noma, I. Naguro, H. Ichijo

The paper shows that zinc deficiency impairs KAT7-dependent H3K14ac at enhancers, upregulating ZIP10 and lipid droplet genes in mice, linking zinc homeostasis to epigenetic regulation.

bioRxiv · Oct 18, 2023Cell Biology

Horizontal transmission of penicillin binding protein 1A caused a nationwide spread of β-lactam resistance in pneumococci

S. Nakano, T. Fujisawa, B. Chang, Y. Ito, N. Kitamura, S. Suga, Y. Matsumura, M. Yamamoto, M. Nagao, M. Ohnishi, M. Sugai

The paper traces the nationwide spread of β-lactam resistance in pneumococci through horizontal transmission of a specific PBP1A variant, highlighting its role in resistance emergence.

bioRxiv · Dec 11, 2022 · PreprintMicrobiology

Image-based taxonomic classification of bulk biodiversity samples using deep learning and domain adaptation

T. Fujisawa, V. Noguerales, E. Meramveliotakis, A. Papadopoulou, A. P. Vogler

This study uses deep learning and domain adaptation to classify bulk invertebrate samples from unexplored ecosystems, showing improved accuracy with standardized imaging and transfer learning.

bioRxiv · Dec 22, 2021Zoology

Structural basis of the protochromic green/red photocycle of the chromatic acclimation sensor RcaE

T. Nagae, M. Unno, T. Koizumi, Y. Miyanoiri, T. Fujisawa, K. Masui, T. Kamo, K. Wada, T. Eki, Y. Ito, Y. Hirose, M. Mishima

This paper reports the crystal structure of RcaE's bilin-binding domain in the red-absorbing state and provides NMR evidence of bilin protonation states, elucidating the structural basis of the green/red photocycle in CBCRs.

bioRxiv · Dec 8, 2020Biochemistry