Author

M. Nagao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Bioengineering· 2 Physiology· 2 Biochemistry· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 7 Organism:human· 6 Organism:mouse· 5 Research Focus:cell signaling & trafficking· 4 Research Focus:cell type annotation· 3 Research Focus:development & morphogenesis· 2 Research Focus:differential expression· 2

Frequent Co-Authors

M. Shinohara· 3 shared M. Yamamoto· 3 shared Y. Matsumura· 3 shared A. Takashima· 2 shared L. Eliasson· 2 shared N. Sakitani· 2 shared S. Murase· 2 shared S. Nakano· 2 shared

Activity by Year

2019-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBioengineering

M. Shinohara

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

Virological characteristics of the SARS-CoV-2 Omicron EG.5.1 variant

S. Tsujino, S. Deguchi, T. Nomai, M. Padilla-Blanco, A. Plianchaisuk, L. Wang, M. M. Begum, K. Uriu, K. Mizuma, N. Nao, I. Kojima, T. Tsubo, J. Li, Y. Matsumura, M. Nagao, , Za

The paper investigates the virological features of the SARS-CoV-2 EG.5.1 variant, finding its fitness and antiviral sensitivity comparable to XBB.1.5, with structural differences in spike proteins.

bioRxiv · Oct 19, 2023Microbiology

Stress-induced vascular remodeling: novel insight into the role of omega-3 fatty acid metabolite, 4-oxoDHA

M. Nishimori, N. Hayasaka, K. Otsui, N. Inoue, M. Nagao, R. Toh, T. Ishida, K. Hirata, T. Furuyashiki, M. Shinohara

This study identifies 4-oxoDHA as a stress-related biomarker linked to vascular inflammation through its regulation of the Nrf2-HO-1 pathway and ICAM-1 expression.

bioRxiv · Jul 25, 2023 · PreprintBiochemistry

Horizontal transmission of penicillin binding protein 1A caused a nationwide spread of β-lactam resistance in pneumococci

S. Nakano, T. Fujisawa, B. Chang, Y. Ito, N. Kitamura, S. Suga, Y. Matsumura, M. Yamamoto, M. Nagao, M. Ohnishi, M. Sugai

The paper traces the nationwide spread of β-lactam resistance in pneumococci through horizontal transmission of a specific PBP1A variant, highlighting its role in resistance emergence.

bioRxiv · Dec 11, 2022 · PreprintMicrobiology

Application of Passive Head Motion to Generate Defined Accelerations at the Heads of Rodents

T. Maekawa, N. Sakitani, Y. Ryu, A. Takashima, S. Murase, J. Fink, M. Nagao, T. Ogata, M. Shinohara, Y. Sawada

This paper develops a passive head motion system to simulate mechanical accelerations from treadmill running in rodents and shows it activates 5-HT2A signaling in the prefrontal cortex.

bioRxiv · Jul 5, 2022Bioengineering

Delayed antigen-specific CD4+ T cell induction correlates with impaired immune responses to SARS-COV-2 mRNA vaccination in the elderly

N. Jo, Y. Hidaka, O. Kikuchi, M. Fukahori, T. Sawada, M. Aoki, M. Yamamoto, M. Nagao, S. Morita, T. E. Nakajima, M. Muto, Y. Hamazaki

The paper examines how delayed CD4+ T cell responses in the elderly correlate with reduced vaccine effectiveness and lower reactogenicity to SARS-CoV-2 mRNA vaccines.

bioRxiv · May 10, 2022 · PreprintImmunology

The structure of insulin granule core determines secretory capacity being reduced in type-2 diabetes

M. Barghouth, X. Jiang, M. Nagao, N. Chen, D. Yang, Y. Ye, C. Luan, M. Gomez, A. M. Blom, C. Wollheim, L. Eliasson, E. Renstrom, E. Zhang

The paper investigates the structure of insulin granule cores and shows that their size reduction in type-2 diabetes correlates with impaired insulin secretion.

bioRxiv · Feb 22, 2022 · PreprintPhysiology

Antihypertensive effect of brain-targeted mechanical intervention with passive head motion

S. Murase, N. Sakitani, T. Maekawa, D. Yoshino, K. Takano, A. Konno, H. Hirai, T. Saito, S. Tanaka, K. Shinohara, T. Kishi, Y. Yoshikawa, T. Sakai, M. Ayaori, H. Inanami, , Y. Sawada

Passive head motion reduces blood pressure in hypertensive rats and humans by decreasing AT1R expression in RVLM astrocytes through interstitial fluid shear stress.

bioRxiv · Sep 21, 2020Bioengineering

Smad3 Regulates Smooth Muscle Cell Fate and Governs Adverse Remodeling and Calcification of Atherosclerotic Plaque

P. Cheng, r. Wirka, J. Kim, T. Nguyen, R. Kundu, q. Zhao, A. Pedroza, M. Nagao, D. Iyer, M. Fischbein, T. Quertermous

This study shows that Smad3 in smooth muscle cells prevents harmful plaque changes in atherosclerosis by blocking specific cell transitions that lead to calcification and inflammation.

bioRxiv · Sep 15, 2020 · PreprintCell Biology

Comparison of 12 molecular detection assays for SARS-CoV-2

Y. Matsumura, T. Shimizu, T. Noguchi, S. Nakano, M. Yamamoto, M. Nagao

The paper compares 12 SARS-CoV-2 molecular assays using respiratory samples, finding some have 100% specificity and high sensitivity, with recommendations for use with internal controls.

bioRxiv · Jun 24, 2020 · PreprintMicrobiology

Exposure to maternal obesity per se programs sex-differences in pancreatic islets of the offspring

L. M. Nicholas, M. Nagao, L. C. Kusinski, D. S. Fernandez-Twinn, L. Eliasson, S. E. Ozanne

The paper examines how maternal obesity affects pancreatic islet function in offspring, revealing sex-specific differences in mitochondrial respiration and apoptosis susceptibility.

bioRxiv · Mar 27, 2019Physiology