T. Matsui

Global trends in biodiversity and ecosystem services from 1900 to 2050

The paper assesses historical and future trends in biodiversity and ecosystem services from 1900 to 2050, finding that biodiversity and regulating services have decreased while provisioning services increased, with climate change expected to worsen future losses.

Structural basis for bispecific antibody design: arrangement of domain linkage produces activity enhancement

This study determines the cryo-EM structures of two bispecific antibody types and shows that domain linkage rearrangement leads to activity enhancement by altering complex shape and dynamics.

Acute Vigorous Exercise Decreases Subsequent Non-Exercise Physical Activity and Body Temperature Linked to Weight Gain

Exercise intensity-dependent lactate elevation in skin interstitial fluid and its long-lasting effect

This study shows that skin interstitial fluid lactate rises with blood lactate during exercise and remains elevated for 30 minutes post-exercise, and can predict lactate threshold.

Growth inhibitory factor/metallothionein-3 is a sulfane sulfur-binding protein

The paper identifies GIF/metallothionein-3 as a sulfane sulfur-binding protein that regulates zinc ion binding and release through a unique C-S-S-Zn structure.

Pathophysiological Significance of Impaired KAT7-Dependent Histone H3K14 Acetylation During Zinc Deficiency

The paper shows that zinc deficiency impairs KAT7-dependent H3K14ac at enhancers, upregulating ZIP10 and lipid droplet genes in mice, linking zinc homeostasis to epigenetic regulation.

Syntaxin 17 recruitment to mature autophagosomes is temporally regulated by PI4P accumulation

The paper shows that STX17 recruitment to mature autophagosomes is temporally regulated by PI4P-driven changes in membrane charge.

Prediction of elimination of intrahepatic cccDNA in hepatitis B virus-infected patients by a combination of noninvasive viral markers

This study develops a noninvasive method using viral markers to predict cccDNA levels in HBV patients, validated against liver biopsy data.

TBC1D18, a novel Rab5-GAP, coordinates endosome maturation together with Mon1

This study identifies TBC1D18 as a novel Rab5-GAP that works with Mon1 to regulate endosome maturation by inactivating Rab5.

Hidden pathway for cytokine receptor activation: Structural insights into a marine sponge-derived lectin that activates the thrombopoietin receptor via recognition of the fucose moiety

A marine sponge-derived lectin activates the thrombopoietin receptor by promoting dimerization and exhibits synergy with thrombopoietin, affecting receptor internalization.

Crocosphaera as a major consumer of fixed nitrogen despite its capability of nitrogen fixation

This study shows Crocosphaera efficiently consumes combined nitrogen sources and maintains high growth rates even when nitrogen is limited, highlighting its ecological importance.

A Ca2+ wave generates a force during cell extrusion in zebrafish

This study shows that a Ca2+ wave in zebrafish generates force during cell extrusion by inducing polarized movements via IP3 receptor and trpc1.

RBD11, a bioengineered Rab11-binding module for visualizing and analyzing endogenous Rab11

This study develops RBD11, a bioengineered Rab11-binding domain that visualizes endogenous Rab11 without disrupting its function and demonstrates its use in analyzing Rab11-dependent processes.

An early-morning flowering trait in rice helps retain grain yield under heat stress field conditions at flowering stage

This study shows that the early-morning flowering trait in rice improves grain yield under heat stress by reducing spikelet sterility.

Why do some primate mothers carry their infant's corpse? A cross-species comparative study

This study examines why some primate mothers carry their infant's corpse, analyzing 409 cases across 50 species and finding no strong predictors for the behavior but a link between infant age and carrying duration.

Canopy micrometeorology monitoring in diverse climates innovatively improves the evaluation heat-induced sterility of rice under climate change

This study evaluates heat-induced sterility in rice using canopy micrometeorology data across diverse climates, showing that panicle temperature can accurately predict sterility rates.

ALIX and ceramide differentially control polarized exosome release from epithelial cells

The paper identifies two distinct mechanisms for polarized exosome release from epithelial cells: ALIX-Syntenin1-Syndecan1 for apical exosomes and ceramide production for basolateral exosomes.

A Bacterial Surface Layer Protein Exploits Multi-step Crystallization for Rapid Self-assembly

This paper shows a bacterial surface layer protein uses a multi-step pathway with a nucleation domain to rapidly crystallize, enabling efficient 2D self-assembly on cell surfaces.

Characterization of coral-associated microbial aggregates (CAMAs) within tissues of the coral Acropora hyacinthus

The paper characterizes coral-associated microbial aggregates (CAMAs) in Acropora hyacinthus tissues, showing their distribution and density vary with distance from the coastline.

A protocol for an intercomparison of biodiversity and ecosystem services models using harmonized land-use and climate scenarios

This paper describes a protocol for comparing biodiversity and ecosystem services models using harmonized land-use and climate scenarios to assess future impacts and model uncertainties.