Author

T. Grancharova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Nelson· 3 shared C. Yan· 3 shared K. A. Gerbin· 3 shared R. N. Gunawardane· 3 shared S. Q. Dinh· 3 shared A. B. Rosenberg· 2 shared A. Haupt· 2 shared A. R. Horwitz· 2 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersCell Biology

A. Nelson

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4 papers

Recent·Most cited

A comprehensive analysis of gene expression changes in a high replicate and open-source dataset of differentiating hiPSC-derived cardiomyocytes

T. Grancharova, K. A. Gerbin, A. B. Rosenberg, C. M. Roco, J. Arakaki, C. DeLizzo, S. Q. Dinh, R. Donovan-Maiye, M. Hirano, A. Nelson, J. Tang, J. A. Theriot, C. Yan, V. Menon, S. P. Palecek, , R. N. Gunawardane

The paper analyzes gene expression changes in hiPSC-derived cardiomyocytes using single-cell RNA-seq, identifying key genes that mark differentiation stages and sources of variation across protocols and cell lines.

bioRxiv · Apr 22, 2021Cell Biology

Robust integrated intracellular organization of the human iPS cell: where, how much, and how variable

M. P. Viana, J. Chen, T. A. Knijnenburg, R. Vasan, C. Yan, J. E. Arakaki, M. Bailey, B. Berry, A. Borensztejn, J. M. Brown, S. Carlson, J. A. Cass, B. Chaudhuri, K. R. Cordes Metzler, M. E. Coston, , Leung

The paper establishes quantitative rules for the locations, amounts, and variation of 25 cellular structures in human iPSCs using high-resolution imaging and analysis.

bioRxiv · Dec 8, 2020 · PreprintCell Biology

Cell states beyond transcriptomics: integrating structural organization and gene expression in hiPSC-derived cardiomyocytes

K. A. Gerbin, T. Grancharova, R. Donovan-Maiye, M. C. Hendershott, J. Brown, S. Q. Dinh, J. L. Gehring, M. Hirano, G. R. Johnson, A. Nath, A. Nelson, C. M. Roco, A. B. Rosenberg, M. F. Sluzewski, M. P. Viana, , R. N. Gunawardane

The paper integrates gene expression and sarcomere organization in hiPSC-derived cardiomyocytes to predict subcellular states and reveal correlations between transcript abundance and structural patterns.

bioRxiv · May 26, 2020Cell Biology

Systematic gene tagging using CRISPR/Cas9 in human stem cells to illuminate cell organization

B. Roberts, A. Haupt, A. Tucker, T. Grancharova, J. Arakaki, M. A. Fuqua, A. Nelson, C. Hookway, S. A. Ludmann, I. M. Mueller, R. Yang, A. R. Horwitz, S. M. Rafelski, R. N. Gunawardane

The paper describes a CRISPR/Cas9 method to tag endogenous proteins in human iPSCs, generating 10 tagged lines with quality-controlled clones for cell biology research.

bioRxiv · Mar 31, 2017Cell Biology