Author

S. P. Palecek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Cell Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 5 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. B. Rosenberg· 2 shared A. Nelson· 2 shared C. M. Roco· 2 shared C. Yan· 2 shared G. Seelig· 2 shared J. A. Theriot· 2 shared K. A. Gerbin· 2 shared M. Hirano· 2 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

A. B. Rosenberg

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Author profile →

5 papers

Recent·Most cited

A comprehensive analysis of gene expression changes in a high replicate and open-source dataset of differentiating hiPSC-derived cardiomyocytes

T. Grancharova, K. A. Gerbin, A. B. Rosenberg, C. M. Roco, J. Arakaki, C. DeLizzo, S. Q. Dinh, R. Donovan-Maiye, M. Hirano, A. Nelson, J. Tang, J. A. Theriot, C. Yan, V. Menon, S. P. Palecek, , R. N. Gunawardane

The paper analyzes gene expression changes in hiPSC-derived cardiomyocytes using single-cell RNA-seq, identifying key genes that mark differentiation stages and sources of variation across protocols and cell lines.

bioRxiv · Apr 22, 2021Cell Biology

Cell states beyond transcriptomics: integrating structural organization and gene expression in hiPSC-derived cardiomyocytes

K. A. Gerbin, T. Grancharova, R. Donovan-Maiye, M. C. Hendershott, J. Brown, S. Q. Dinh, J. L. Gehring, M. Hirano, G. R. Johnson, A. Nath, A. Nelson, C. M. Roco, A. B. Rosenberg, M. F. Sluzewski, M. P. Viana, , R. N. Gunawardane

The paper integrates gene expression and sarcomere organization in hiPSC-derived cardiomyocytes to predict subcellular states and reveal correlations between transcript abundance and structural patterns.

bioRxiv · May 26, 2020Cell Biology

Adaptable pulsatile flow generated by quantitative imaging of stem-cell derived cardiomyocytes for disease modeling

T. Qian, D. A. Gil, E. Contreras Guzman, B. D. Gastfriend, K. E. Tweed, S. P. Palecek, M. C. Skala

This study introduces an adaptable pump system to generate pulsatile flows from cardiac spheroids, enabling modeling of endothelial cell behavior under different mechanical stresses.

bioRxiv · Mar 20, 2020Bioengineering

Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function, drug penetration, and antibody shuttling properties

T.-E. Park, N. Mustafaoglu, A. Herland, R. M. Hasselkus, R. Mannix, E. A. FitzGerald, R. Prantil-Baun, A. Watters, O. Henry, M. Benz, H. Sanchez, H. J. McCrea, L. Christova Goumnerova, H. W. Song, S. P. Palecek, , D. E. Ingber

This paper develops a BBB chip that maintains high barrier function for a week, enabling better drug and antibody testing.

bioRxiv · Nov 29, 2018 · PreprintBioengineering

Preventing S. aureus biofilm formation on titanium surfaces by the release of antimicrobial β-peptides from polyelectrolyte multilayers

A. de L. Rodriguez Lopez, M.-R. Lee, R. Whitehead, D. M. Lynn, S. P. Palecek

This paper develops β-peptide-containing chitosan/hyaluronic acid films to prevent S. aureus biofilm formation on titanium surfaces, showing long-term antimicrobial activity without cytotoxicity.

bioRxiv · Sep 30, 2018Bioengineering