Author

T. Hamakubo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:ATAC-seq· 1 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Yamashita· 1 shared B. P. Berman· 1 shared D.-C. Lin· 1 shared E.-M. Li· 1 shared H. Iwanari· 1 shared H. P. Koeffler· 1 shared J. Pan· 1 shared J. Plummer· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

A. Yamashita

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Author profile →

2 papers

Recent·Most cited

Structure and mechanism of oxalate transporter OxlT in an oxalate-degrading bacterium in the gut microbiota

T. Jaunet-Lahary, T. Shimamura, M. Hayashi, N. Nomura, K. Hirasawa, T. Shimizu, M. Yamashita, K. Kojima, Y. Sudo, T. Tamura, H. Iwanari, T. Hamakubo, S. Iwata, K.-i. Okazaki, T. Hirai, A. Yamashita

This study determines the crystal structures of OxlT, an oxalate transporter, and reveals its mechanism for selective oxalate uptake and exclusion of other carboxylates.

bioRxiv · Nov 15, 2021Biochemistry

Lineage-Specific Epigenomic and Genomic Activation of the Oncogene HNF4A Promotes Gastrointestinal Adenocarcinomas

J. Pan, T. C. Silva, N. Gull, Q. Yang, J. Plummer, S. Chen, K. Daigo, T. Hamakubo, S. Gery, L.-W. Ding, Y.-Y. Jiang, S.-Y. Hu, L.-Y. Xu, E.-M. Li, Y. Ding, , D.-C. Lin

The paper identifies lineage-specific activation of HNF4A in gastrointestinal adenocarcinomas through epigenomic and genomic analysis, revealing its role in promoting cancer proliferation.

bioRxiv · Oct 21, 2019Cancer Biology