T. Hirai

Generation of a porcine cell line stably expressing pig TMPRSS2 for efficient isolation of viruses from pigs with respiratory diseases

Development of a non-invasive method for testicular toxicity evaluation using a novel compact magnetic resonance imaging system

The paper demonstrates a compact MRI system for non-invasive testicular toxicity evaluation in mice, showing reduced testicular volume and increased signal intensity after busulfan treatment.

Integrated Analysis of T cell Repertoire and Transcriptome Identifies Mechanisms of Regulatory T cell (Treg) Suppression of Acute Graft-versus-Host-Disease

This study identifies how regulatory T cells suppress acute graft-versus-host disease by modulating conventional T cell transcriptomes and metabolism without affecting graft-versus-tumor activity.

Structure and mechanism of oxalate transporter OxlT in an oxalate-degrading bacterium in the gut microbiota

This study determines the crystal structures of OxlT, an oxalate transporter, and reveals its mechanism for selective oxalate uptake and exclusion of other carboxylates.

Allogeneic CAR-invariant Natural Killer T Cells Exert Potent Antitumor Effects Through Host CD8 T cell Cross-Priming

This study shows allogeneic CAR-iNKT cells effectively combat tumors in mice by directly attacking cancer cells and boosting host CD8 T cell responses, even across major MHC barriers.