M. Yamashita

This paper develops a high-throughput 3D imaging flow cytometry platform for analyzing spheroid models on hydrogel beads, revealing adhering cells have smaller nuclei with non-round surfaces.

This paper identifies celery UGT94AX1 as the apiosyltransferase responsible for apiin biosynthesis and characterizes its substrate specificity and key residues.

This study identifies PRC1.1 as a regulator of homeostatic and emergency myelopoiesis, showing its role in balancing myeloid differentiation and preventing transformation.

The paper investigates a human Orai1 mutation causing tubular aggregate myopathy and shows that Ca2+-dependent inactivation (CDI) of CRAC channels can occur independently of STIM1.

This study develops a droplet array platform to track single-cell extracellular vesicle secretion dynamics over time, revealing heterogeneity and the role of cell division in EV secretion.

This study determines the crystal structures of OxlT, an oxalate transporter, and reveals its mechanism for selective oxalate uptake and exclusion of other carboxylates.

This study finds that patients with severe SARS-CoV-2 disease have higher antibody titers against viral proteins and neutralization capabilities compared to less severe cases.