K. Kojima

Effects of tenascin-C on dental pulp tissue in mice in vivo and on the proliferation and differentiation of dental pulp stem cells into odontoblasts and calcification in vitro

This study examines the effects of tenascin-C on dental pulp tissue in mice and on the differentiation of dental pulp stem cells into odontoblasts, showing reduced inflammation and altered calcification.

Can Colpoda travel across oceans? Salinity tolerance of resting cysts may enable global dispersal of the species.

The study investigates whether Colpoda cucullus resting cysts can tolerate saline conditions, suggesting a mechanism for oceanic dispersal of freshwater protists.

Essential role of an acidic endosomal environment in JAK3-mediated signal transduction

This study shows that acidic endosomal environments are essential for JAK3-mediated signal transduction and that IAVNs like chloroquine and monensin disrupt this process, affecting cytokine signaling and arthritis.

Hemopexin Reverses Activation of Lung eIF2a and Decreases Mitochondrial Injury in Chlorine Exposed Mice

This study shows that hemopexin reduces acute lung injury and mitochondrial damage in chlorine-exposed mice by reversing eIF2α activation and mtDNA lesions.

Collection of 2429 constrained headshots of 277 volunteers for deep learning

The paper collects 2429 constrained headshots of 277 volunteers for deep learning, demonstrating its utility for gender recognition with convolutional neural networks.

Proton-pumping rhodopsins in marine diatoms

This study identifies diatom rhodopsin as a light-driven proton pump localized to plastid membranes and suggests it contributes to a CO2-concentrating mechanism in diatoms.

Structure and mechanism of oxalate transporter OxlT in an oxalate-degrading bacterium in the gut microbiota

This study determines the crystal structures of OxlT, an oxalate transporter, and reveals its mechanism for selective oxalate uptake and exclusion of other carboxylates.

Proton-mediated gating mechanism of anion channelrhodopsin-1

The paper investigates the proton-mediated gating mechanism of GtACR1 by analyzing mutants and using computational methods to determine the protonation states and their effects on absorption wavelengths.

Mesenchymal Stromal Cell Aging Impairs the Self-Organizing Capacity of Lung Alveolar Epithelial Stem Cells

This study shows that aging of lung mesenchymal stromal cells impairs the ability of alveolar epithelial stem cells to form 3D organoids, and that reducing Nox4 activity can partially reverse this effect.

Changes choroidal area following trabeculectomy: long-term effect of intraocular pressure reduction

This study examines how intraocular pressure reduction after trabeculectomy affects choroidal areas, finding increased macular and peripapillary choroidal areas with significant interstitial area expansion.