Author

R. Kibbey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:metabolism & bioenergetics· 3 Assay:metabolomics· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

T. Alves· 2 shared A. K. Jha· 1 shared A. Perdigoto· 1 shared B. Stutz· 1 shared B. Willard· 1 shared C. Hoppel· 1 shared C. J. Greenbaum· 1 shared C. Speake· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersCell Biology

T. Alves

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Citrullination of glucokinase linked to autoimmune diabetes

M.-L. Yang, S. Horstman, R. Gee, P. Guyer, T. Lam, J. Kanyo, A. Perdigoto, C. Speake, C. J. Greenbaum, L. Overbergh, R. Kibbey, K. C. Herold, E. A. James, M. J. Mamula

This study identifies citrullination of glucokinase as an inflammatory-driven PTM that triggers autoimmunity and impairs glucose metabolism in Type 1 diabetes.

bioRxiv · Apr 28, 2021Immunology

Mitochondrial fission governed by Drp1 regulates exogenous fatty acid usage and storage

J. E. Song, T. Alves, B. Stutz, M. Sestan-Pesa, N. Kilian, S. Diano, R. Kibbey, T. Horvath

This study shows that mitochondrial fission, regulated by Drp1, influences how cells balance the use and storage of exogenous fatty acids.

bioRxiv · Oct 17, 2020Cell Biology

Integrated Metabolomic and Transcriptomic Profiling Reveals Novel Activation-Induced Metabolic Networks in Human T cells

S. E. Hiemer, S. Jatav, J. Jussif, J. Alley, S. Lathwal, M. A. Piotrowski, J. Janiszewski, R. Kibbey, T. Alves, D. Dumlao, A. K. Jha, H. Bandukwala

This study integrates metabolomic and transcriptomic data to identify metabolic networks in human T cells and shows that targeting these pathways can enhance immunosuppressive drug efficacy.

bioRxiv · Jul 16, 2019 · PreprintImmunology

Discovery of a redox-thiol switch regulating cellular energy metabolism

X.-H. Gao, L. Li, M. Parisien, M. Mcleod, J. Wu, I. Bederman, Z. Gao, D. Krokowski, S. M. Chirieleison, L. Diatchenko, D. Abbott, V. Yee, C. Hoppel, R. Kibbey, T. Holyoak, , M. Hatzoglou

The paper identifies a Redox Thiol Switch (RTSGS) that regulates cellular energy metabolism by switching between S-glutathionylation and S-sulfhydration, with PCK2 as a novel target.

bioRxiv · Jan 14, 2019 · PreprintBiochemistry