T. Katayama

Anisotropic regulation of lateral surface tension directs invagination in C. elegans gastrulation

The paper shows that anisotropic lateral surface tension, mediated by HMR-1/E-cadherin, directs invagination in C. elegans gastrulation, complementing apical constriction.

Human Milk Oligosaccharide Utilization in Intestinal Bifidobacteria is Governed by a Global Transcriptional Regulator NagR

This study identifies NagR as a global transcriptional regulator governing HMO utilization pathways in B. infantis, revealing its role in regulating multiple HMO catabolic pathways and evolutionary adaptation.

Mitochondrial fission dysfunction alleviates heterokaryon incompatibility-triggered cell death in the industrial filamentous fungus Aspergillus oryzae

This study investigates incompatibility-triggered cell death in Aspergillus oryzae by showing that mitochondrial fission dysfunction alleviates cell death during incompatible heterokaryon formation.

AMPK regulates cell shape of cardiomyocytes by modulating turnover of microtubules through CLIP-170

This study shows AMPK regulates cardiomyocyte shape by modulating microtubule turnover via CLIP-170 phosphorylation at intercalated discs.

Butyrate producing Clostridiales utilize distinct human milk oligosaccharides correlating to early colonization and prevalence in the human gut

The paper identifies HMO utilization pathways in Roseburia and Eubacterium that enable co-growth with Akkermansia muciniphilia and highlight distinct HMO utilization phylotypes in the early gut microbiota.

Breastmilk-promoted bifidobacteria produce aromatic lactic acids in the infant gut

This study identifies aromatic lactic acids produced by breastmilk-promoted Bifidobacterium in the infant gut and shows their role in modulating immune responses via AhR and HCAR3.

Membrane-bounded nucleoid discovered in a cultivated bacterium of the candidate phylum ‘Atribacteria’

The paper reports the discovery of a membrane-bounded nucleoid in a cultivated bacterium from the candidate phylum Atribacteria, challenging the traditional view of prokaryotic cell structure.