T. S. Matsui

A model explaining environmental stiffness-dependent migration of fibroblasts with a focus on maturation of intracellular structures

The paper develops a mathematical model to explain how fibroblast migration velocity depends on substrate stiffness through changes in stress fiber maturation and contractile force.

Long-term molecular turnover of actin stress fibers revealed by advection-reaction analysis in fluorescence recovery after photobleaching

This study develops a new FRAP model to analyze long-term molecular turnover, revealing that advection and chemical reaction rates are comparable in actin stress fibers.

Proteome of actin stress fibers

The paper identifies the proteome of actin stress fibers in human fibroblasts and shows that eEF2 is upregulated with replicative senescence, contributing to SF reinforcement.

Wrinkle force microscopy: a new machine learning based approach to predict cell mechanics from images

This paper introduces a machine learning method to predict cellular forces from microscope images by training on wrinkle patterns and traction force data.

Determining the domain-level reaction-diffusion properties of cellular proteins by incorporating genetic engineering to FRAP-based framework

This paper introduces a FRAP-based framework with genetic engineering to determine domain-level reaction and diffusion properties of proteins, demonstrating its application to transgelin-2.

Statistical profiling reveals correlations between the cell response to and structural sequence of Rho-GAPs

The paper analyzes the correlation between the morphological response of cells to Rho-GAP silencing and their structural sequence similarity.

AMPK regulates cell shape of cardiomyocytes by modulating turnover of microtubules through CLIP-170

This study shows AMPK regulates cardiomyocyte shape by modulating microtubule turnover via CLIP-170 phosphorylation at intercalated discs.