T. Kojima

Spatiotemporal dynamics and ossification of podoplanin-positive cells in the developing femur

This study investigates the spatiotemporal dynamics and role of podoplanin-positive cells in fetal femur development, finding they contribute to coordinated bone formation.

Functional studies of deafness-associated pendrin and prestin variants

The paper functionally characterizes deafness-associated pendrin and prestin variants using in vitro assays to assess their pathogenic impacts.

Basement membrane extract potentiates the endochondral ossification phenotype of bone marrow-derived mesenchymal stem cell-based cartilage organoids

This study shows that basement membrane extract enhances endochondral ossification in bone marrow-derived mesenchymal stem cell-based cartilage organoids by altering gene expression and pathway activation.

Rapid and cost-effective epitope mapping using PURE ribosome display coupled with next-generation sequencing and bioinformatics

The paper develops a cost-effective method for epitope mapping using PURE ribosome display combined with NGS and bioinformatics, identifying the 'DVPDY' epitope in hemagglutinin.

AtMYB50 regulates root cell elongation by upregulating PECTIN METHYLESTERASE INHIBITOR 8 in Arabidopsis thaliana

The paper identifies MYB50 as a transcription factor regulated by UPB1 that promotes root cell elongation by upregulating PMEI8 in Arabidopsis thaliana.

Biochemical reactions between intra-articular tissues and joint instability in a rat model of osteoarthritis

This study investigates the role of joint instability in osteoarthritis progression using a rat model, finding that joint instability exacerbates cartilage degeneration and that TGF-β1 inhibition may reduce synovial inflammation.

Nascent MSKIK peptide prevents or releases translation arrest in Escherichia coli

The paper shows that inserting the MSKIK peptide near a start codon enhances protein production in E. coli by preventing or releasing translational arrest.

cDNA display coupled with next-generation sequencing for rapid activity-based screening: Comprehensive analysis of transglutaminase substrate preference

The paper develops a cDNA display combined with next-generation sequencing platform to analyze transglutaminase 2 substrate preferences, revealing comprehensive amino acid preferences at specific peptide positions.