S. Okamoto

Basement membrane extract potentiates the endochondral ossification phenotype of bone marrow-derived mesenchymal stem cell-based cartilage organoids

This study shows that basement membrane extract enhances endochondral ossification in bone marrow-derived mesenchymal stem cell-based cartilage organoids by altering gene expression and pathway activation.

Willingness of Japanese people in their 20s, 30s and 40s to pay for genetically modified foods

This study compares willingness-to-pay for GM foods among Japanese adults aged 20-40, finding lower WTP for animal-derived GM products compared to plant and ornamental GM items.

Definitive environmental DNA research on aquatic insects: Analysis optimization using the recently developed MtInsects-16S primers set

This study develops and validates MtInsects-16S primers for eDNA analysis of aquatic insects, showing improved detection of target species and reduced amplification of nontarget taxa.

Context-Dependent Modification of PFKFB3 in Hematopoietic Stem Cells Promotes Anaerobic Glycolysis and Ensures Stress Hematopoiesis

This study identifies PFKFB3 as a key regulator of glycolytic metabolism in HSCs under stress, showing its context-dependent activation promotes ATP production and hematopoiesis.

Isolation and genomic and physiological characterization of Parageobacillus sp. G301, the isolate capable of both hydrogenogenic and aerobic carbon monoxide oxidation

This paper isolates and characterizes Parageobacillus sp. G301, a novel CO oxidizer capable of both hydrogenogenic and aerobic CO oxidation using both Ni-CODH and Mo-CODH.

Regulation of ammonium acquisition and use in Oryza longistaminata ramets under nitrogen source heterogeneity

Oryza longistaminata regulates ammonium acquisition and use in response to spatial nitrogen heterogeneity through inter-ramet communication.

Preclinical study of DNA vaccines targeting SARS-CoV-2

This study evaluates a DNA vaccine targeting SARS-CoV-2 Spike protein, showing enhanced humoral and cellular immune responses and neutralizing antibody activity.

GP96 drives exacerbation of secondary bacterial pneumonia following influenza A virus infection

This study shows that GP96 promotes pneumococcal adherence to IAV-infected epithelial cells, leading to bacterial pneumonia, and that inhibiting GP96 reduces lung infection and pathology.

State-space Modeling Clarifies Productivity Regime Shifts of Japanese Flying Squid

The paper develops a state-space model to detect regime shifts in Japanese flying squid productivity, showing significant changes in maximum sustainable yields around 1991 and 2015.