Author

T. Kouno

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

J. W. Shin· 2 shared T. Suzuki· 2 shared A. Kumanogoh· 1 shared A. Minoda· 1 shared D. M. Standley· 1 shared G. Pascarella· 1 shared H. Okano· 1 shared H. Suzuki· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

J. W. Shin

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2 papers

Recent·Most cited

CiDRE+ M2c macrophages hijacked by SARS-CoV-2 cause COVID-19 severity

Y. Mitsui, T. Suzuki, K. Kuniyoshi, J. Inamo, K. Yamaguchi, M. Komuro, J. Watanabe, M. Edamoto, S. Li, T. Kouno, S. Oba, T. Hosoya, S. Koyama, N. Sakaguchi, D. M. Standley, , T. Satoh

This study identifies IL-10-driven M2c macrophages as key contributors to severe COVID-19 by facilitating SARS-CoV-2 infection and highlights CiDRE as a potential therapeutic target.

bioRxiv · Sep 30, 2022 · PreprintImmunology

Single-cell transcriptomics reveals expansion of cytotoxic CD4 T-cells in supercentenarians

K. Hashimoto, T. Kouno, T. Ikawa, N. Hayatsu, Y. Miyajima, H. Yabukami, T. Terooatea, T. Sasaki, T. Suzuki, M. Valentine, G. Pascarella, Y. Okazaki, H. Suzuki, J. W. Shin, A. Minoda, , P. Carninci

This study identifies an increase in cytotoxic CD4 T-cells and a reduction in B-cells in supercentenarians through single-cell transcriptomics.

bioRxiv · May 20, 2019Immunology