Author

M. Valentine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Evolutionary Biology· 1 Immunology· 1 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

D. M. Engelthaler· 3 shared C. M. Hepp· 2 shared A. Bahrami· 1 shared A. Minoda· 1 shared A. Naranjo· 1 shared A. Pappo· 1 shared A. Shelat· 1 shared B. Brock· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersMicrobiology

D. M. Engelthaler

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Discovery and Repurposing of Pharmaceutical Agents as Antifungals: In vivo activity against Coccidioides

H. Mead, M. Valentine, G. R. Thompson, H. Yin, P. Keim, D. M. Engelthaler, B. M. Barker

The paper tests existing drugs for antifungal activity against Coccidioides in mice, finding that sertraline combined with fluconazole reduces lung fungal load.

bioRxiv · Feb 21, 2024 · PreprintMicrobiology

Lyssa excreta: Defining parameters for fecal samples as a rabies virus surveillance method

F. M. Walker, J. R. Upton, D. Erickson, Z. A. Barrand, B. Brock, M. Valentine, E. L. Federman, E. M. Froehlich, L. I. Van Pelt, L. Hastings, D. L. Bergman, D. M. Engelthaler, C. M. Hepp

This study tests the viability of using fecal samples for rabies virus surveillance by assessing RNA persistence and detection rates in bats.

bioRxiv · May 27, 2023Pathology

Single-cell transcriptomics reveals expansion of cytotoxic CD4 T-cells in supercentenarians

K. Hashimoto, T. Kouno, T. Ikawa, N. Hayatsu, Y. Miyajima, H. Yabukami, T. Terooatea, T. Sasaki, T. Suzuki, M. Valentine, G. Pascarella, Y. Okazaki, H. Suzuki, J. W. Shin, A. Minoda, , P. Carninci

This study identifies an increase in cytotoxic CD4 T-cells and a reduction in B-cells in supercentenarians through single-cell transcriptomics.

bioRxiv · May 20, 2019Immunology

MYCN Amplification and ATRX Mutations are Incompatible in Neuroblastoma

M. Zeineldin, S. Federico, X. Chen, Y. Fan, B. Xu, E. Stewart, X. Zhou, J. Jeon, L. Griffiths, J. Easton, H. Mulder, D. Yergeau, Y. Liu, J. Wu, C. Van Ryn, , M. Dyer

The paper shows that ATRX mutations and MYCN amplification are mutually exclusive in neuroblastoma and lead to synthetic lethality.

bioRxiv · Jul 29, 2018Cancer Biology

Phylogenetic analysis of West Nile Virus in Maricopa County, Arizona: Evidence for dynamic behavior of strains in two major lineages in the American Southwest

C. M. Hepp, J. H. Cocking, M. Valentine, S. J. Young, D. Damian, K. Sheridan, V. Y. Fofanov, J. D. Busch, D. E. Erickson, R. C. Lancione, K. Smith, J. Will, J. Townsend, P. S. Keim, D. M. Engelthaler

The paper analyzes WNV strains in Maricopa County, Arizona, showing two major lineages with dynamic behavior, including local overwintering of NA/WN02 strains.

bioRxiv · Nov 22, 2017Evolutionary Biology