Author

J. W. Shin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

T. Kouno· 2 shared T. Suzuki· 2 shared A. Kumanogoh· 1 shared A. Minoda· 1 shared D. D. Kao· 1 shared D. H. Ryu· 1 shared D. M. Standley· 1 shared F. Lopez-Giraldez· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersImmunology

T. Kouno

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Functional immune state classification of unlabeled live human monocytes using holotomography and machine learning

M. Lee, G. Kim, M. S. Lee, J. W. Shin, J. H. Lee, D. H. Ryu, Y. S. Kim, Y. Chung, K. S. Kim, Y. Park

This study uses holotomography and machine learning to classify functional immune states of human monocytes, achieving high accuracy in identifying hyper-inflammatory and immune-suppressed states.

bioRxiv · Sep 12, 2023 · PreprintImmunology

CiDRE+ M2c macrophages hijacked by SARS-CoV-2 cause COVID-19 severity

Y. Mitsui, T. Suzuki, K. Kuniyoshi, J. Inamo, K. Yamaguchi, M. Komuro, J. Watanabe, M. Edamoto, S. Li, T. Kouno, S. Oba, T. Hosoya, S. Koyama, N. Sakaguchi, D. M. Standley, , T. Satoh

This study identifies IL-10-driven M2c macrophages as key contributors to severe COVID-19 by facilitating SARS-CoV-2 infection and highlights CiDRE as a potential therapeutic target.

bioRxiv · Sep 30, 2022 · PreprintImmunology

Single-cell transcriptomics reveals expansion of cytotoxic CD4 T-cells in supercentenarians

K. Hashimoto, T. Kouno, T. Ikawa, N. Hayatsu, Y. Miyajima, H. Yabukami, T. Terooatea, T. Sasaki, T. Suzuki, M. Valentine, G. Pascarella, Y. Okazaki, H. Suzuki, J. W. Shin, A. Minoda, , P. Carninci

This study identifies an increase in cytotoxic CD4 T-cells and a reduction in B-cells in supercentenarians through single-cell transcriptomics.

bioRxiv · May 20, 2019Immunology

Differential functional roles of fibroblasts and pericytes in the formation of tissue-engineered microvascular networks in vitro

N. Kosyakova, D. D. Kao, F. Lopez-Giraldez, S. Spindler, M. Graham, K. J. James, J. W. Shin, X. Liu, G. T. Tietjen, J. S. Pober, W. G. Chang

This study compares the roles of fibroblasts and pericytes in supporting endothelial cell self-assembly into perfusable microvascular networks in vitro.

bioRxiv · Feb 22, 2019Cell Biology