T. Mioka

The CWI pathway is activated through high hydrostatic pressure, enhancing glycerol efflux via the aquaglyceroporin Fps1 in Saccharomyces cerevisiae

This study shows high hydrostatic pressure activates the CWI pathway in yeast, leading to increased glycerol efflux via Fps1 to counteract osmotic stress.

Phospholipid flippases and Sfk1 are essential for the retention of ergosterol in the plasma membrane

This study shows that phospholipid flippases and Sfk1 are essential for retaining ergosterol in the yeast plasma membrane, with their disruption leading to sterol accumulation in lipid droplets.

Phosphatidylserine prevents the generation of a protein-free giant plasma membrane domain in yeast

The paper shows that yeast lacking phosphatidylserine form protein-free plasma membrane domains, termed void zones, which resemble artificial lipid domains.