T. Fujimoto

Fetal Kidney Transplantation for In Utero Fetuses

This paper describes a novel fetal therapy approach using transplanted fetal kidneys from different species to provide a bridge to dialysis in affected fetuses, demonstrating successful urine production and long-term function without immunosuppressants.

Physicochemical properties of the vacuolar membrane and cellular factors determine formation of vacuolar invaginations

The paper shows that vacuolar invaginations in yeast result from changes in membrane physicochemical properties and cellular factors like Hfl1 and the ESCRT machinery.

On-grid labeling method for freeze-fracture replicas

This paper introduces an on-grid labeling method for freeze-fracture replicas to simplify SDS-FRL by reducing manual labor and enabling storage and pre-labeling checks.

Lysosomal microautophagic pathway links proteostasis to protein aggregation disease

This study identifies SIDT2 as a mediator of microautophagy that delivers cytosolic proteins into lysosomes, linking proteostasis to protein aggregation disease.

Phosphatidylserine prevents the generation of a protein-free giant plasma membrane domain in yeast

The paper shows that yeast lacking phosphatidylserine form protein-free plasma membrane domains, termed void zones, which resemble artificial lipid domains.

ESCRT machinery mediates selective microautophagy of endoplasmic reticulum

This study identifies the ESCRT machinery and Nem1-Spo7 phosphatase complex as key components mediating micro-ER-phagy in yeast, distinguishing it from macro-ER-phagy.

Syntaxin 17 promotes lipid droplet formation by regulating the distribution of acyl-CoA synthetase 3

The paper shows syntaxin 17 regulates lipid droplet formation by controlling the distribution of ACSL3, with SNAP23 mediating its release during maturation.