Author

T. S. Kaminski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Approach:deep learning· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Assay:flow cytometry· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

F. Hollfelder· 4 shared A. Lulla· 1 shared C. Deane· 1 shared D. Schnettler Fernandez· 1 shared E. J. Medcalf· 1 shared F. Leiss-Maier· 1 shared F. Nintzel· 1 shared J. C. Yam-Puc· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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4 shared papersBiochemistry

F. Hollfelder

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Ultrahigh throughput evolution of tryptophan synthase in droplets via an aptamer-biosensor

R. Scheele, Y. Weber, F. Nintzel, M. Herger, T. S. Kaminski, F. Hollfelder

This paper develops a DNA aptamer biosensor to enable high-throughput screening of tryptophan synthase variants in droplets, identifying 5-fold improved enzymes.

bioRxiv · Oct 11, 2023 · PreprintBiochemistry

Microfluidics-enabled fluorescence-activated cell sorting of single pathogen-specific antibody secreting cells for the rapid discovery of monoclonal antibodies

K. Fischer, A. Lulla, T. So, P. Pereyra-Gerber, M. I. J. Raybould, T. N. Kohler, T. S. Kaminski, J. C. Yam-Puc, R. Hughes, F. Leiss-Maier, P. Brear, N. J. Matheson, C. Deane, M. Hyvonen, J. Thaventhiran, F. Hollfelder

This paper presents a microfluidics-based method to rapidly discover monoclonal antibodies from antigen-specific antibody secreting cells, achieving high-affinity and neutralizing antibodies against SARS-CoV-2.

bioRxiv · Jan 10, 2023Immunology

Ultrahigh-throughput Absorbance Activated Droplet Sorting (UHT-AADS) for enzyme screening at kilohertz frequencies

E. J. Medcalf, M. Gantz, T. S. Kaminski, F. Hollfelder

This paper introduces UHT-AADS, a method that improves absorbance-based droplet sorting speed to match fluorescence sorting, enhancing enzyme screening throughput.

bioRxiv · Sep 13, 2022 · PreprintBiochemistry

Ultrahigh-throughput directed evolution of a metal-free α/β-hydrolase with a Cys-His-Asp triad into an efficient phosphotriesterase

D. Schnettler Fernandez, O. J. Klein, T. S. Kaminski, P.-Y. Colin, F. Hollfelder

This paper evolves a metal-free α/β-hydrolase with a Cys-His-Asp triad into an efficient phosphotriesterase using ultrahigh-throughput screening, achieving catalytic efficiencies comparable to metal-dependent enzymes.

bioRxiv · Feb 14, 2022Biochemistry