Author

T. Shirai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Evolutionary Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Approach:statistical model· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1

Frequent Co-Authors

A. Kondo· 2 shared C. J. Vavricka· 1 shared D. K. Summers· 1 shared D. Yano· 1 shared D.-i. Kato· 1 shared E. Sivaniah· 1 shared H. Ohashi· 1 shared H. Shibata· 1 shared

Activity by Year

2016-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersPlant Biology

A. Kondo

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Dark accumulation of downstream glycolytic intermediates confers robust initiation of photosynthesis in cyanobacteria

K. Tanaka, T. Shirai, C. J. Vavricka, M. Matsuda, A. Kondo, T. Hasunuma

The paper shows that accumulation of glycolytic intermediates in the dark enables rapid initiation of photosynthesis in cyanobacteria.

bioRxiv · Apr 4, 2022 · PreprintPlant Biology

Multidrug treatment with nelfinavir and cepharanthine against COVID-19

H. Ohashi, K. Watashi, W. Saso, K. Shionoya, S. Iwanami, T. Hirokawa, T. Shirai, S. Kanaya, Y. Ito, K. S. Kim, K. Nishioka, S. Ando, K. Ejima, Y. Koizumi, T. Tanaka, , T. Wakita

This study identifies a new multidrug combination treatment for COVID-19 using nelfinavir and cepharanthine, showing synergistic antiviral effects and improved disease control.

bioRxiv · Apr 14, 2020 · PreprintMicrobiology

Resurrecting the ancient glow

Y. Oba, K. Konishi, D. Yano, H. Shibata, D.-i. Kato, T. Shirai

This study reconstructs ancestral firefly luciferase genes and finds the last common ancestor emitted green light, likely for aposematic display.

bioRxiv · Sep 23, 2019 · PreprintEvolutionary Biology

Metabolomic and proteomic analyses of a quiescent Escherichia coli cell factory reveal the mechanisms behind its production efficiency

N. M. Thomson, T. Shirai, M. Chiapello, A. Kondo, K. J. Mukherjee, E. Sivaniah, D. K. Summers, K. Numata

The paper investigates quiescent Escherichia coli cultures to reveal how indole-induced quiescence enhances metabolite production efficiency.

bioRxiv · Oct 20, 2016Microbiology