Author

T. Hirokawa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Approach:deep learning· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

H. Inoue· 2 shared T. Suzuki· 2 shared A. Nakamura· 1 shared A. Yamamoto· 1 shared F. Yumoto· 1 shared H. Kojima· 1 shared H. Ohashi· 1 shared J. McKeating· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersPharmacology & Toxicology

H. Inoue

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pseudoirreversible inhibition elicits persistent efficacy of a sphigosine-1-phosphate receptor-1 antagonist

Y. Maruyama, Y. Ohsawa, T. Suzuki, Y. Yamauchi, K. Ohno, H. Inoue, A. Yamamoto, M. Hayashi, Y. Okuhara, W. Muramatsu, K. Namiki, M. Miyauchi, T. Miyao, N. Hagiwara, T. Ishikawa, , T. Akiyama

This study identifies KSI-6666 as a pseudoirreversible S1PR1 antagonist that suppresses inflammation through interaction with a methionine residue.

bioRxiv · May 8, 2023 · PreprintPharmacology & Toxicology

Multidrug treatment with nelfinavir and cepharanthine against COVID-19

H. Ohashi, K. Watashi, W. Saso, K. Shionoya, S. Iwanami, T. Hirokawa, T. Shirai, S. Kanaya, Y. Ito, K. S. Kim, K. Nishioka, S. Ando, K. Ejima, Y. Koizumi, T. Tanaka, , T. Wakita

This study identifies a new multidrug combination treatment for COVID-19 using nelfinavir and cepharanthine, showing synergistic antiviral effects and improved disease control.

bioRxiv · Apr 14, 2020 · PreprintMicrobiology

An integrated approach unravels a crucial structural property for the function of the insect steroidogenic Halloween protein Noppera-bo

K. Koiwai, K. Inaba, K. Morohashi, S. Enya, R. Arai, H. Kojima, T. Okabe, Y. Fujikawa, H. Inoue, R. Yoshino, T. Hirokawa, K. Kato, K. Fukuzawa, Y. Shimada-Niwa, A. Nakamura, , R. Niwa

This paper determines the structure of the insect steroidogenic Halloween protein Noppera-bo and identifies a conserved residue critical for its function.

bioRxiv · Sep 27, 2019Biochemistry