Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
8 papers
Recent·Most cited
S. Chavez-Abiega, M. L. B. Gronloh, T. W. J. Gadella…·J. Goedhart
The paper investigates cell-to-cell heterogeneity in ERK and Akt activation by GPCRs, showing distinct dynamics depending on the activated G proteins.
F. H. van der Linden, E. K. Mahlandt, J. J. G. Arts…·J. Goedhart
This paper introduces a new calcium biosensor based on fluorescence lifetime imaging, which provides accurate and pH-insensitive quantification of intracellular calcium concentrations.
E. K. Mahlandt, J. J. G. Arts, W. J. van der Meer…·J. Goedhart
The paper improves RhoA localization-based biosensors to better detect endogenous RhoA activity in various cellular processes.
N. R. Reinhard, S. van der Niet, A. O. Chertkova…·J. Goedhart
The paper quantifies Cdc42 activation by endothelial GEFs in primary human cells, identifying FGD1 as the most selective activator.
M. Mastop, N. R. Reinhard, C. R. Zuconelli…·J. Goedhart
The paper develops a FRET-based biosensor to measure Gα13 activation in single cells and demonstrates its use in detecting receptor-induced responses.
M. Mastop, D. S. Bindels, N. C. Shaner…·J. Goedhart
The paper evaluates fluorescent proteins as FRET acceptors for mTurquoise2, identifying mNeonGreen as the most efficient and photostable pair.
J. van Unen, D. Botman, T. Yin…·J. Goedhart
This study shows that membrane association of TGAT is critical for its activity, but palmitoylation is not required for membrane localization or RhoA activation.