Author

T. Wakabayashi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biochemistry· 1 Evolutionary Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:plant (other)· 2 Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Matsusaki· 1 shared A. Muto· 1 shared A. Okazawa· 1 shared C. K. Skovbjerg· 1 shared D. Ohta· 1 shared E. Fukai· 1 shared E. Joyashiki· 1 shared F. Azuma· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperBioengineering

A. Matsusaki

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Complete suspension culture of human induced pluripotent stem cells supplemented with suppressors of spontaneous differentiation

M. Matsuo-Takasaki, S. Kambayashi, Y. Hemmi, T. Wakabayashi, T. Shimizu, Y. An, H. Ito, K. Takauchi, M. Ibuki, T. Kawashima, R. Masayasu, M. Suzuki, N. Nishishita, Y. Kawai, M. Umekage, , Y. Hayashi

This study develops a suspension culture method for hiPSCs using PKCβ and Wnt inhibitors to prevent spontaneous differentiation, enabling scalable and stable clinical-grade hiPSC production.

bioRxiv · Oct 8, 2023Bioengineering

Insights into stereoselective ring formation in canonical strigolactone: Discovery of a dirigent domain-containing enzyme catalyzing orobanchol synthesis

M. Homma, T. Wakabayashi, Y. Moriwaki, N. Shiotani, T. Shigeta, K. Isobe, A. Okazawa, D. Ohta, T. Terada, K. Shimizu, M. Mizutani, H. Takikawa, Y. Sugimoto

This study identifies a dirigent domain-containing enzyme, SRF, that catalyzes the stereoselective BC-ring closure in orobanchol biosynthesis, revealing the molecular mechanism for SL stereochemistry.

bioRxiv · Aug 7, 2023 · PreprintPlant Biology

A bispecific antibody NXT007 exerts a hemostatic activity in hemophilia A monkeys enough to keep a non-hemophiliac state

Y. Teranishi-Ikawa, T. Soeda, H. Koga, K. Yamaguchi, K. Kato, K. Esaki, K. Asanuma, M. Funaki, M. Ichiki, Y. Ikuta, S. Ito, E. Joyashiki, S.-I. Komatsu, A. Muto, K. Nishimura, , T. Igawa

This paper reports a bispecific antibody NXT007 that shows improved hemostatic activity in hemophilia A monkeys, equivalent to FVIII levels, with lower dosing requirements and longer intervals.

bioRxiv · Dec 19, 2022Bioengineering

Cryo-EM structures of cardiac thin filaments reveal the 3D architecture of troponin.

T. Oda, H. Yanagisawa, T. Wakabayashi

This study determines the 3D structure of murine cardiac thin filaments using cryo-EM with a Volta phase plate, revealing troponin's orientation and interactions with actin and tropomyosin.

bioRxiv · Jan 15, 2020Biochemistry

Extreme genetic signatures of local adaptation during plant colonization

N. Shah, T. Wakabayashi, Y. Kawamura, C. K. Skovbjerg, M.-Z. Wang, Y. Mustamin, Y. Isomura, V. Gupta, H. Jin, T. Mun, N. Sandal, F. Azuma, E. Fukai, U. Seren, S. Kusakabe, , S. U. Andersen

The paper investigates genetic adaptations during the colonization of Japan by Lotus japonicus, identifying genomic regions and candidate genes associated with overwintering and flowering time traits.

bioRxiv · Dec 11, 2018Evolutionary Biology