M. Homma

Structural analysis of S-ring composed of FliFG fusion proteins in marine Vibrio polar flagellar motors

The paper reports the near-atomic structure of the S-ring from Vibrio alginolyticus flagellar motor using cryo-EM, revealing structural differences compared to Salmonella.

Roles of linker region flanked by transmembrane and peptidoglycan binding region of PomB in energy conversion of the Vibrio flagellar motor

This study investigates the role of the flexible linker and plug region of PomB in the activation of the sodium-driven flagellar motor stator complex in Vibrio, showing that these regions are important for regulation but not essential for motor function.

Deciphering the Genomes of Motility-Deficient Mutants of Vibrio alginolyticus 138-2

This study identifies mutations in flagella-related genes in motility-deficient Vibrio alginolyticus mutants through genomic analysis.

Insights into stereoselective ring formation in canonical strigolactone: Discovery of a dirigent domain-containing enzyme catalyzing orobanchol synthesis

This study identifies a dirigent domain-containing enzyme, SRF, that catalyzes the stereoselective BC-ring closure in orobanchol biosynthesis, revealing the molecular mechanism for SL stereochemistry.

Ring formation by Vibrio fusion protein composed of FliF and FliG, MS-ring and C-ring component of bacterial flagellar motor in membrane

This study constructs a FliF-FliG fusion protein that enables MS-ring formation in E. coli, revealing its role in flagellar motor assembly and force generation.

Interaction of FlhF, SRP-like GTPase with FliF, MS ring component assembling the initial structure of flagella in marine Vibrio

This paper demonstrates that FlhF interacts with the N-terminal region of FliF, including the first transmembrane segment and periplasmic region, to facilitate MS-ring formation in Vibrio alginolyticus flagella.

Function and structure of FlaK, a master regulator of the polar flagellar genes in marine Vibrio

This study investigates FlaK's role in regulating flagellar gene expression in Vibrio alginolyticus through mutational analysis and biochemical assays, revealing its ATPase activity and interactions with FlhG.

Formation of multiple flagella caused by a mutation of the flagellar rotor protein FliM in Vibrio alginolyticus

This study identifies an E9K mutation in FliM that causes multiple flagella in Vibrio alginolyticus by inhibiting FlhG ATPase activity, revealing a novel regulatory mechanism for flagellar number control.

Functional analysis of the N-terminal region of Vibrio FlhG, a MinD-type ATPase in flagellar number control

The paper investigates the role of the N-terminal region of Vibrio FlhG in flagellar number control by analyzing its effect on FlhF activity and protein levels.

Hoop-like role of the cytosolic interface helix in Vibrio PomA, an ion-conducting membrane protein, in the bacterial flagellar motor

This study investigates the function of the cytosolic interface helix in Vibrio PomA, showing its role in stator complex stability and ion conduction.

ZomB is essential for chemotaxis of Vibrio alginolyticus by the rotational direction control of the polar flagellar motor

This study shows ZomB is essential for clockwise rotation of the flagellar motor in Vibrio alginolyticus, working with CheY to control rotational direction.

Function of the Vibrio PomB plug region based on the stator rotation model for bacterial flagellar motor

The paper investigates the function of the Vibrio PomB plug region by showing it interacts with PomA and terminates ion flow, supporting the stator rotation model.

Site-directed crosslinking identifies the stator-rotor interaction surfaces in a hybrid bacterial flagellar motor

This study uses site-directed crosslinking to directly demonstrate physical interactions between specific residues in FliG and PomA/MotA in bacterial flagellar motors.

Role of the N- and C-terminal regions of FliF, the MS ring component in Vibrio flagellar basal body

This study investigates the roles of N- and C-terminal regions of FliF in Vibrio flagellar MS ring formation and function, finding that the N-terminus aids in ring formation via FlhF interaction while the C-terminus is essential for motor function.

The flagellar motor of Vibrio alginolyticus undergoes major structural remodeling during rotational switching

This study uses cryo-electron tomography to show that the C-ring of Vibrio alginolyticus undergoes structural remodeling during rotational switching.

Dynamic production and loss of flagellar filaments during the bacterial life cycle

This study shows that bacterial flagella are not permanent structures, dynamically produced and lost during growth phases, with glucose availability influencing their disassembly.

The Vibrio H-ring facilitates the outer membrane penetration of polar-sheathed flagellum

This study identifies the H-ring as a novel structure facilitating outer membrane penetration and flagellar assembly in Vibrio alginolyticus using cryo-electron tomography.