Cardiac progenitors auto-regulate second heart field cell fate via Wnt secretion
Matthew Miyamoto, Suraj Kannan, Matthew J. Anderson, Xihe Liu, David Suh, Myo Htet, Biyi Li, Tejasvi Kakani, Sean A. Murphy, Emmanouil Tampakakis, Mark B. Lewandoski, Peter Andersen, Hideki Uosaki, Chulan Kwon
The paper identifies cardiac progenitors as a source of Wnts that regulate second heart field development through secretion, using genetic manipulation and single-cell RNA sequencing in mice.
Proceedings of the National Academy of Sciences · Jan 17, 2023Peer-reviewedDevelopmental Biology