Author

Thomas Simonet

Lyon 1 Université

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Laurent SchaefferiD· 2 shared Armelle CorpetiD· 1 shared Béatrice GrangeiD· 1 shared Camille CoheniD· 1 shared Claire BardeliD· 1 shared Coline SeurreiD· 1 shared Constance KleijwegtiD· 1 shared Delia CicciarelloiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersDevelopmental Biology

Laurent SchaefferORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

LSD1 controls a nuclear checkpoint in Wnt/β-catenin signaling to regulate muscle stem cell self renewal

Sandrine Mouradian, Delia Cicciarello, Nicolas Lacoste, Valérie Risson, Francesca Berretta, Fabien Le Grand, Nicolas Rose, Thomas Simonet, Laurent Schaeffer, Isabella Scionti

This study identifies LSD1 as a regulator of Wnt/β-catenin signaling by demethylating β-catenin to prevent its degradation, thereby influencing muscle stem cell self-renewal.

Nucleic Acids Research · Jan 18, 2024Peer-reviewedDevelopmental Biology

Interplay between PML NBs and HIRA for H3.3 dynamics following type I interferon stimulus

Constance Kleijwegt, Florent Bressac, Coline Seurre, Wilhelm Bouchereau, Camille Cohen, Pascale Texier, Thomas Simonet, Laurent Schaeffer, Patrick Lomonte, Armelle Corpet

The paper identifies SUMO-SIM interactions as essential for HIRA recruitment to PML NBs and shows PML NBs regulate HIRA distribution and H3.3 deposition at ISGs during IFN-I response.

eLife · May 5, 2023Peer-reviewedGenetics

Performances of targeted RNA-sequencing for the analysis of fusion transcripts, gene mutation and expression in haematological malignancies.

Sandrine Hayette, Béatrice Grange, Maxime Vallée, Claire Bardel, Sarah Huet, Isabelle Mosnier, Kaddour Chabane, Thomas Simonet, Marie Balsat, Maël Heiblig, Isabelle Tigaud, Franck Emmanuel Nicolini, Sylvain Mareschal, Gilles Salles, Pierre Sujobert

This study evaluates targeted RNA sequencing for detecting fusion transcripts, mutations, and expression in hematological malignancies, finding it effective for diagnosing leukemia subtypes and identifying most DNA mutations at the mRNA level.

bioRxiv · Sep 7, 2020 · PreprintGenomics