Author
National Institutes of HealthORCID 0000-0001-5967-1296Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Angels Almenar‐Queralt, Isabella Rodrigues Fernandes, Janaina S de Souza…·Alysson Renato Muotri
This study shows that SETD5 dysfunction in astrocytes increases IL-6, which harms neurons via JAK/STAT signaling, suggesting therapeutic targeting of this pathway for ASD and ID.
Danyyl Ippolitov, Yi-Han Lin, Jeremy Spence (21351782)…·Sabine Hombach‐Klonisch
This study establishes a patient-derived HER2+ brain metastasis model and identifies Poziotinib as an effective RTKi for treating HER2+ breast cancer brain metastasis in mice.
Darian Williams, Logan M. Glasstetter, Tiffany T. Jong…·Yu Chen
This paper develops high-throughput assays to identify and optimize small-molecule stabilizers of misfolded β-glucocerebrosidase, showing NCGC326 reverses pathological accumulation and synergizes with proteostasis regulators.