Tonatiuh Peña

This study identifies SOX1-OT as a lncRNA that regulates p53-dependent cell-cycle arrest in astrocytes, with implications for Alzheimer's disease.

This study identifies two clusters of severe mental disorder patients with differing illness severity, finding elevated pro-inflammatory serum proteins in the more severe group.

The paper identifies NeuID, a novel neuron-specific lncRNA downregulated in Alzheimer's disease, as a key regulator of neuronal identity and a therapeutic target.

This study identifies 3222401L13Rik as an aging-upregulated lncRNA in astrocytes that enhances neuronal support through interaction with Npas3, suggesting it may delay age-related cognitive decline.

This study identifies PRDM16-DT as an astrocyte-specific lncRNA downregulated in Alzheimer's disease, showing its role in maintaining astrocyte function and neuronal support.

This study analyzes single-cell transcriptomes of the mouse hippocampus after voluntary exercise, identifying molecular changes related to neurogenesis and signaling pathways.

The paper identifies a novel miR-99b-5p-Zbp1 pathway in microglia that contributes to schizophrenia pathogenesis and suggests potential therapeutic strategies.