Sophie Schröder

The lncRNA Gm16685/MITA1 modulates inflammatory astrocyte reactivity through PCBP2 associated regulation of IKKβ signaling

The paper identifies Gm16685/MITA1 as a lncRNA that regulates astrocyte reactivity through PCBP2-mediated modulation of IKKβ signaling in inflammatory conditions.

NeuID, a novel neuron-specific lncRNA, resolved a key epigenetic mechanisms linking gene silencing to Alzheimer's disease

The paper identifies NeuID, a novel neuron-specific lncRNA downregulated in Alzheimer's disease, as a key regulator of neuronal identity and a therapeutic target.

A role for astrocytic miR-129-5p in Frontotemporal Dementia

This study identifies miR-129-5p as a deregulated microRNA in FTD patients, showing its role in astrocyte dysfunction and neurodegeneration.

PRDM16-DT is a Brain and Astrocyte-Specific lncRNA Implicated in Alzheimers Disease

This study identifies PRDM16-DT as an astrocyte-specific lncRNA downregulated in Alzheimer's disease, showing its role in maintaining astrocyte function and neuronal support.

Postnatal SETD1B is essential for learning and the regulation of neuronal plasticity genes

This study shows that SETD1B is crucial for learning and regulates neuronal plasticity genes in the postnatal brain through H3K4me3 modification.