Dual agonistic and antagonistic roles of ZC3H18 provides for co-activation of distinct nuclear RNA decay pathways
Patrik Polák, William Garland, Om Singh Rathore, Manfred Schmid, Anna Salerno-Kochan, Lis Jakobsen, Maria Gockert, Piotr Gerlach, Toomas Silla, Jens Andersen, Elena Conti, Torben Heick Jensen
The paper identifies dual roles of ZC3H18 in promoting NEXT and antagonizing PAXT to co-activate RNA decay pathways for short substrates.
Cell Reports · Oct 25, 2023Peer-reviewedMolecular Biology