Sivakama S. Bharathi

This study shows that feeding mice odd-chain dicarboxylic acids reproduces the biochemical features of glutaric aciduria type-1.

This study investigates systemic metabolic changes in a mouse model of left ventricular hypertrophy, finding that exogenous long-chain fatty acid supplementation improves mitochondrial function but does not fully reverse the disease phenotype.

This study shows that oral octanoylcarnitine improves exercise tolerance and reduces metabolic stress in mouse models of long-chain fatty acid oxidation disorders.

This study shows that loss of LCAD protects against acute kidney injury by reducing oxidative stress and enhancing peroxisomal fatty acid oxidation.

Maternal administration of mitochondrial-targeted JP4-039 mitigates fetal brain injury and preserves mitochondrial function after mid-gestation radiation exposure.