Author

U. Schlattner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Physiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:metabolism & bioenergetics· 3 Research Focus:cell signaling & trafficking· 2 Assay:metabolomics· 2 Organism:mouse· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

A. Le Gouellec· 2 shared C. G. R. Perry· 2 shared M. Tokarska-Schlattner· 2 shared N. Zeaiter· 2 shared R. Abi Nahed· 2 shared S. Khochbin· 2 shared V. Cunin· 2 shared A. Achouri· 1 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

A. Le Gouellec

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Disrupted cardiac bioenergetics linked to oxidized mitochondrial creatine kinase are rescued by the mitochondrial-targeting peptide SBT-20 in the D2.mdx model of Duchenne muscular dystrophy

C. G. R. Perry, M. C. Hughes, S. V. Ramos, A. Brahmbhatt, P. C. Turnbull, N. Polidovitch, M. C. Garibotti, U. Schlattner, T. J. Hawke, J. A. Simpson, P. H. Backx

This paper investigates how mitochondrial bioenergetics are affected in D2.mdx mice and shows that SBT-20 can improve creatine-dependent bioenergetics by reducing oxidative stress.

bioRxiv · Feb 4, 2024 · PreprintPhysiology

Cytosolic acetyl-CoA synthetase (ACSS2) does not generate butyryl- and crotonyl-CoA

N. Zeaiter, L. Belot, V. Cunin, R. Abi Nahed, M. Tokarska-Schlattner, A. Le Gouellec, C. Petosa, S. Khochbin, U. Schlattner

The paper shows ACSS2 does not generate butyryl- or crotonyl-CoA from SCFAs, challenging previous assumptions about its substrate specificity.

bioRxiv · Dec 21, 2023 · PreprintBiochemistry

FRET-based sensor for measuring adenine nucleotide binding to AMPK

R. Abi Nahed, M. Pelosse, F. Aulicino, F. Cottaz, I. Berger, U. Schlattner

The paper describes an AMPK-based FRET sensor, AMPfret, that detects conformational changes in AMPK upon nucleotide binding, enabling analysis of AMPK activation in vitro and in cells.

bioRxiv · Sep 5, 2023 · PreprintBiochemistry

Multi-method quantification of acetyl-CoA and further acyl-CoA species in normal and ischemic rat liver

M. Tokarska-Schlattner, N. Zeaiter, V. Cunin, S. Attia, C. Meunier, L. Kay, A. Achouri, E. Hiriart-Bryant, K. Couturier, C. Tellier, A. El Harras, B. Elena-Herrmann, S. Khochbin, A. Le Gouellec, U. Schlattner

The paper compares methods to quantify acyl-CoA species in rat liver under normal and ischemic conditions, finding ischemia affects short chain acyl-CoA concentrations differently based on duration.

bioRxiv · Sep 4, 2023Biochemistry

Muscle weakness precedes atrophy during cancer cachexia and is associated with muscle-specific mitochondrial stress

L. J. Delfinis, C. A. Bellissimo, S. Gandhi, S. N. DiBenedetto, M. E. Rosa-Caldwell, F. A. Rahman, M. P. Wiggs, U. Schlattner, J. Quadrilatero, N. P. Greene, C. G. R. Perry

This study shows muscle weakness occurs before atrophy in mice with cancer cachexia and is linked to muscle-specific mitochondrial changes.

bioRxiv · Sep 15, 2021 · PreprintPhysiology