Author

Ulrike Froehlich

Université de Sherbrooke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 1 Approach:mixed model· 1 Organism:rat· 1

Frequent Co-Authors

Malihe Hassanzadeh· 2 shared Pierre‐Luc BoudreaultiD· 2 shared Richard LeduciD· 2 shared Alexandre Joushomme· 1 shared Alexandre MurzaiD· 1 shared Alice Gravel-Trudeau· 1 shared Antoine DésiletsiD· 1 shared Brian J. HolleraniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Malihe Hassanzadeh

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Tunable Bias Signaling of the Angiotensin II Type 1 Receptor for Inotropy via C-Terminal Peptide Modifications and Allosteric Site Targeting

Margot Hadjadj, Justin Martel, Marie-Frédérique Roy, Malihe Hassanzadeh, Hugo Giguère, Alexandre Murza, Brian J. Holleran, Yoon Namkung, Ulrike Froehlich, Richard Leduc, Mannix Auger‐Messier, Stéphane A. Laporte, Pierre‐Luc Boudreault

This study identifies AngII analogs with modified C-terminal peptides that selectively engage Gq or β-arrestin pathways, showing differential effects on cardiac function and blood pressure in rats.

bioRxiv · Aug 13, 2025 · PreprintMolecular Biology

Development of ketobenzothiazole-based peptidomimetic TMPRSS13 inhibitors with low nanomolar potency

Alexandre Joushomme, Antoine Désilets, William Champagne, Malihe Hassanzadeh, Gabriel Lemieux, Alice Gravel-Trudeau, Matthieu Lepage, Sabrina Lafrenière, Ulrike Froehlich, Karin List, Pierre‐Luc Boudreault, Richard Leduc

This study identifies low nanomolar TMPRSS13 inhibitors through chemical library screening and molecular modeling, showing their ability to block SARS-CoV-2 pseudovirus entry.

Journal of Enzyme Inhibition and Medicinal Chemistry · Feb 20, 2025Peer-reviewedPharmacology & Toxicology