Peripheral Neuronal Activation Shapes the Microbiome and Alters Gut Physiology
J. A. Griffiths, B. B. Yoo, P. Thuy-Boun, V. Cantu, K. Weldon, C. Challis, M. J. Sweredoski, K. Y. Chan, T. M. Thron, G. Sharon, A. Moradian, G. Humphrey, Q. Zhu, J. Shaffer, D. W. Wolan, , S. Mazmanian
This study activates specific gut neurons in mice to show they influence microbiome structure and gut physiology, including bile acids and fecal output, without brain signals.
bioRxiv · Apr 12, 2021Physiology